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05.11.18
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When you get the opportunity to celebrate, what are some things you enjoy?

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Although there was "very high" overlap (97%) between individuals who were identified as having PTSD on ICD-10 and ICD-11 criteria, ICD-11 identified "only about half as many participants as ICD-10 across assessment intervals," Barbano said. Specifically, 47% to 57% fewer individuals were diagnosed with PTSD under ICD-11 criteria.

In addition, the severity of PTSD symptoms identified by ICD-11 criteria (CAPS total scores) was 31% to 36% higher than those identified by ICD-10 criteria alone. "However, those who were identified only by the ICD-10 still had CAPS scores that were indicative of moderate or threshold PTSD, so pretty symptomatic," Barbano said. On the basis of these findings, she suggested that ICD-11 might miss the moderate cases.

These results suggest clinicians should use caution in strictly applying ICD-11 PTSD criteria, she said.

http://game-megaupload.com/Kircher-brother-of-Gadsby-from-rsta?Cheverezs=133
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In the study, as part of ongoing surveillance, the researchers from Key Laboratory of Sichuan Province, Sichuan University collected rectal swabs from randomly selected chickens in multiple commercial in China.

The researchers found that E. coli from the chickens often carried multiple genes, including one copy of the colistin-resistance gene mcr-1, and one copy of the resistance gene, mcr-3. This is the first report of these two genes on a single . "The coexistence of mcr-1 and mcr-3 in E. coli isolates may pose a huge threat to public health," said Dr. Hongning Wang, Ph.D., Professor of Animal Disease Prevention and Food Safety, Key Laboratory of Sichuan Province, Sichuan University.

Plasmids are genetic elements that can jump from one bacterium to another, and sometimes even from one species to another, often spreading resistance genes.

The resistance genes were contained on a type of plasmid known as IncP. The researchers also found circular pieces of DNA bearing mcr-3, which were derived from IncP plasmids. These so-called circular intermediates often contain "insertion sequences" that encourage their integration into other plasmids, hastening spread of the resistance genes.

"This study was originally designed to isolate strains carrying mcr-1 genes, but it is surprising that there are already strains carrying multiple mcr genes in chicken farms," said Dr. Wang. "The apparent spread of the same IncP plasmid with one or two mcr genes between different species and a patient, the hospital environment, and animal production is worrying, he said.

The mcr colistin resistance , five of which are now known, were only discovered in 2016 (there are also variants on some of the five.) In addition to E. coli, the have been found in Klebsiella pneumoniae, Enterobacteriaceae, and aeromonads.

"It is time to let the public understand the serious consequences of the abuse of antibiotics," said Dr. Wang. Antibiotic overuse occurs when antibiotics are used to promote growth in livestock, and when doctors prescribe them unnecessarily. "If the last line of is breached by bacteria, we will find ourselves in the post-antibiotic era."

Explore further: New resistance mechanism in the often multidrug resistant pathogen Acinetobacter baumannii